Professional ear wax removal Henley
Henley hearing Clinic are a certified ear wax removal centre based in Henley Bucks. If you are suffering from blocked ears, excessive ear wax and need this the be relieved then please call our Chalfont or Henley centres for an appointment. Leon Cox the lead audiologist can assist in ascertaining the ear wax issue and clear the ear blockage. Using Microsuction for the ear wax removal is the simplest and easiest way although if preferred we can use the traditional water irrigation technique.
If you need or want a hearing test this also can be conducted at the either branch, along with information on the very latest digital hearing aids by the major manufacturers.
The Henley hearing Clinic is a premium independent hearing centre serving the whole of Buckinghamshire.
Beaconsfield hearing aids
The Henley Hearing Clinic covers the whole of Buck including Beaconsfield and Amersham, Watford, Harpsden, Twyford. Suppliers of high end digital hearing aids including hearing accessories, hearing aid batteries and ear wax removal. Leon Cox the lead audiologist at The Henley Hearing Clinic is a highly experienced expert on hearing and hearing tests. Please book an appointment if you need Micro-suction ear wax removal.
Henley Hearing Clinc News:
Original story by:The Hearing Review
Researchers Identify Gene Associated with Age-related Hearing Loss
An international group of researchers, led by Ronna Hertzano, MD, PhD, associate professor, Department of Otorhinolaryngology-Head & Neck Surgery, at the University of Maryland School of Medicine (UMSOM), and Michael Bowl, PhD, program leader track scientist, Mammalian Genetics Unit, MRC Harwell Institute, UK, have identified the gene that acts as a key regulator for special cells needed in hearing.
The discovery of this gene (Ikzf2) will help researchers better understand this unique type of cell that is needed for hearing and potentially develop treatments for common age-related hearing loss, UMSOM announced.
Bucks hearing aids
“Outer hair cells are the first inner ear cells lost as we age,” said Hertzano, whose research will be published in the journal Nature. “Age-related hearing loss happens to everyone. Even a 30-year-old has lost some of the outer hair cells that sense higher pitch sounds. Simple exposure to sound, especially loud ones, eventually causes damage to these cells.”
The inner ear has two kinds of sensory hair cells required for hearing. The inner hair cells convert sounds to neural signals that travel to the brain. This compares to outer hair cells, which function by amplifying and tuning sounds. Without outer hair cells, sound is severely muted and inner hair cells don’t signal the brain. Loss of outer hair cells is said to be the major cause of age-related loss of hearing.
About the Research
Hertzano’s group, in collaboration with Ran Elkon, PhD, senior lecturer, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine in Tel Aviv, Israel, took a bioinformatics and functional genomics approach to discover a gene critical for the regulation of genes involved in outer hair cell development. Bowl’s group studied mice from the Harwell Aging Screen to identify mice with hearing loss. Bowl identified mice with an early-onset hearing loss caused by an outer hair cell deficit. When the two groups realized that they were studying the same gene, they began to collaborate to discover its biological function and role in outer hair cell development. The gene is Ikzf2 gene, which encodes helios. Helios is a transcription factor, a protein that controls the expression of other genes. The mutation in the mice changes one amino acid in a critical part of the protein, which impaired the transcriptional regulatory activity of helios in the mice.
Micro-suction wax removal Bucks
To test if helios could drive the differentiation of outer hair cells, the researchers introduced a virus engineered to overexpress helios into the inner ear hair cells of newborn mice. As a result, some of the mature inner hair cells became more like outer hair cells. In particular, the inner hair cells with an excess of helios started making the protein prestin and exhibited electromotility, a property limited to outer hair cells. Thus, helios can drive inner hair cells to adopt critical outer hair cell characteristics.
Funding for the research was provided by Action on Hearing Loss UK, the National Institute on Deafness and Other Communication Disorders (NIDCD) at the National Institutes of Health, and the Department of Defense (DOD).
As Professor Steve Brown, PhD, director, MRC Harwell Institute, said, “The development of therapies for age-related hearing loss represents one of the big challenges facing medicine and biomedical science. Understanding the genetic programs that are responsible for the development and maturation of sound-transducing hair cells within the inner ear will be critical to exploring avenues for the regeneration of these cells that are lost in abundance during age-related hearing loss. The teams from the University of Maryland and the MRC Harwell Research Institute have given us the first insights into that program. They have identified a master regulator, Ikzf2/helios, that controls the program for maturation of outer hair cells. Now, we have a target that we can potentially use to induce the production of outer hair cells within damaged inner ears, and we are one step closer to offering treatments for this disabling condition.”
Original Paper: Chessum L, Matern MS, Kelly MC, et al. Helios is a key transcriptional regulator of outer hair cell maturation. Nature. November 21, 2018.
Source: University of Maryland School of Medicine, Nature
Image: University of Maryland School of Medicine
Ear wax removal, Bucks
Do you live in Bucks? In need of a hearing test or your hearing aid repaired? Or maybe you need your ear wax removed by a leading ear wax removal centre? Here at the Hearing clinic Henley, Leon Cox can help with all your hearing needs.
Ear wax removal Buckinghamshire
We are experts in ear wax removal and use various techniques. Micro-suction is just one way we can get out your hard impacted ear wax and the traditional water irrigation is another. You can watch our video on Micro-suction here.
Tinnitus therapy in Bucks
DID YOU KNOW?
1 in 10 adults in the UK suffer with tinnitus.
Many of those suffering are not offered any help, and are simply told to live with it.
Tinnitus can almost always be improved for the client.
How can we help with Tinnitus?
We firstly meet with you and sit and discuss your full hearing history, work out what triggered the problem, we then talk to you about evaluating the degree of tinnitus and how it is impacting on your life, where your issues are. We normally examine the ears with our video otoscope and show you the results on our flat screen. We then carry out a puretone audiogram to assess how good your hearing is, or if there are any areas of damage (such as those caused by noise for example).
We then sit down and consult with you, armed with all the information, and work out a care plan for you, using the tools available to us as explained above.
Please call our clinic for an appointment and we will fit you in as soon as possible. We are based in Henley on Thames.
Henley independent hearing
The Henley hearing clinic and ear wax removal centre is a premier independent local hearing service in Bucks. We believe in personal service, we offer premier hearing tests and ear wax removal. Using the latest knowledge and using the latest tech we know how to perform the very best hearing tests.
We stock hearing aid batteries, and conduct hearing tests onsite here in Henley.
Henley hearing clinic news:
Widex Announces New Insights into EVOKE Hearing Aid’s AI Function
Widex announced the first data gathered from the WIDEX EVOKE™ hearing aid, which is said to achieve “a new level of Artificial Intelligence (AI)” through machine learning, and is helping to bring new insights into how users are taking control of their sound environment to improve their hearing experience, according to the company.
Ear wax removal Henley
Denmark-based Widex launched the WIDEX EVOKE hearing aid in April. The hearing aid is reportedly the first to give users the ability to employ real-time machine learning that can solve the tricky hearing problems that users face in their daily lives.
“We launched WIDEX EVOKE with SoundSense technology to put users back in control of the most difficult hearing situations,” said Jens Brehm Nielsen, data science & machine learning architect at Widex. “And we can see that EVOKE users have taken the opportunity to do that and, in the process, are helping us understand more about them. That information will help us to make the EVOKE and future hearing aids even better.”
Henley hearing aids
SoundSense Learn is an AI system, because AI is said to refer to systems that solve tasks humans are inherently good at—such as driving a car, doing the dishes, etc. SoundSense Learn expands into entirely new applications by helping end users adjust their hearing aids in the moment, reportedly something that no humans can replicate to the same degree of accuracy, according to Widex.
The SoundSense Learn smartphone app is connected to the EVOKE hearing aids and uses machine learning to guide users in optimizing the settings to their exact needs. The app gathers a variety of anonymous data such as how often they turn the volume up or down, which sound presets they use, and how many custom settings they create—including those made with SoundSense Learn.
Hearing test in Henley
Tagging of custom settings has proved to be one of the interesting pieces of data generated by EVOKE.
“We found that many people have created a setting and tagged it with, for instance, ‘work’ which suggests that it is something that our end users need and want,” said Nielsen. “And from SoundSense Learn we already have an idea of how they like the settings.”
Some hearing aids give users the ability to customize their sound experience by adjusting frequency bands to boost or cut bass, middle or high tones. Adjusting frequencies works well in many situations once the initial settings have been set by a skilled audiologist. However, some situations are so complex that hitting the right combination of adjustments can be difficult.
“Widex hearing aids are well known for the quality of their sound,” said Nielsen. “But SoundSense Learn has added an extra layer of quality sound on top of that by using a machine learning algorithm together with reinforcement learning—the two key ingredients in state-of-the art AI algorithm, that enables the algorithm to learn in the moment.
“The algorithm learns an optimal setting every time a user finds the sound to be a little below expectations in a given sound environment. It learns these settings by simply asking the user to compare two settings that are carefully picked by the algorithm. This allows it to learn an optimal setting in a new environment very fast.”
By collating and analyzing the anonymous data WIDEX EVOKE will continue to become even smarter as time passes.
Depression and Hearing Loss
Henley Hearing Clinic News:
Depression and its connection to hearing loss seems pretty logical and self-evident, especially if you’re a dispensing professional who experiences daily the difference that amplification can make in a person’s life. In fact, many clinicians find themselves explaining the connection as follows: a person’s hearing loss and related communication problems can lead to gaffes and social faux pas; leading to embarrassment, anxiety, and loss of self-esteem; leading to gradual withdrawal from social situations and physical activity; leading to social isolation and loneliness; and eventually bringing them down the path to depression.
While this is probably an adequate description for some cases, a recent webinar1 by Victor Bray, PhD, associate professor and former dean of Salus University’s Osborne College of Audiology, points to more recent scientific literature that paints a far more complex picture of hearing loss and its association with depression—one we all should be aware of. The utility of hearing aids, cochlear implants, and assistive devices is made no less important by this complexity; however, it’s vital to understand who might be most at risk for depression in your patient population, how best to administer simple screening tools (ie, the PHQ-2 or PHQ-9), and why it’s important to refer patients to a medical doctor or psychologist, when indicated.
Depression, also known as major depressive disorder (MDD), is present in 5-10% of the general population (up to 40% in some groups), and is a serious medical illness that negatively affects feelings, thoughts, and actions. The primary risk factors for depression are co-morbid chronic medical conditions (hearing loss is a pervasive chronic condition, especially among seniors) and recent stressful events. And, as with cognitive decline and dementia—the subject of my editorial last month—the stakes in treating depression are high for society and healthcare professionals. As Hsu and colleagues (2016) pointed out:
Depression is a common mental disorder, which affects 350 million people in the world. Unipolar depressive disorders and adult-onset hearing loss, the most common neuropsychiatric conditions, and sense organ disorder, respectively, are the first and second leading nonfatal causes of year loss due to disability among adults in high-income countries.2
Several of the studies reviewed by Dr Bray tend to suggest that the odds ratio for acquiring depression increases by a factor of about two if you have untreated hearing loss. However, a lot of the studies also show that a variety of chronic illnesses—ranging from cirrhosis to diabetes mellitus—can be associated with depression, so there could be some underlying neurophysiological common cause in hearing loss and other health problems that hasn’t been discovered yet. Dr Bray also looks at some very intriguing research about how dual-sensory loss (ie, hearing and vision loss) and sudden sensorineural hearing loss (particularly among young people) can greatly increase the risk for depression, as well as studies that are shedding light on how treated hearing loss might positively affect those suffering from anxiety, loneliness, and depression.
As Dr Bray explains, the linkage of hearing loss to depression could come from both a social (downstream) effect, as described at the beginning of this article, and a biological/neurological (upstream) effect, as proposed in a model by Rutherford et al.3 If that were the case, an effective treatment plan could involve therapy and/or medication from a psychologist, in coordination with a hearing device and/or auditory and cognitive retraining from a hearing care professional.
Dr Bray’s webinar was sponsored by Hamilton CapTel, and the company also sponsored an exceptionally interesting and well-viewed webinar last year about hearing loss and associated co-morbidities (including depression) by Harvey Abrams, PhD.4,5 When viewed together, they put an exclamation point on the fact that hearing loss isn’t just about the ears, it’s about health, the brain, quality of life, healthy aging, and so much more—while underscoring the crucial role of the hearing care professional in general healthcare.
To see Dr Bray’s webinar, visit https://bit.ly/2Lpt4AW.
Citation for this article: Strom KE. Depression and hearing loss. Hearing Review. 2018;25(8):6.
1. Bray V. Depression, hearing loss, and treatment with hearing aids [Webinar]. July 13, 2018. Available at: http://www.hearingreview.com/2018/07/new-webinar-depression-hearing-loss-treatment-hearing-aids
2. Hsu W-T, Hsu C-C, Wen M-H, et al. Increased risk of depression in patients with acquired sensory hearing loss: A 12-year follow-up study. Medicine. 2016;95(44):e5312.
3. Rutherford BR, Brewster K, Golub JS, Kim AH, Roose SP. Sensation and psychiatry: Linking age-related hearing loss to late-life depression and cognitive decline. Am J Psychiatry. 2017;175(3):215-224.
4. Abrams H. Hearing loss and associated comorbidities: What do we know [Webinar]? May 31, 2017. Available at: http://www.hearingreview.com/2017/05/new-webinar-hearing-loss-associated-comorbidities-know/
5. Abrams H. Hearing loss and associated comorbidities: What do we know? Hearing Review. 2017;24(12):32-35. Available at: http://www.hearingreview.com/2017/11/hearing-loss-associated-comorbidities-know/